產品屬性:
產品名稱 | Reticulol |
規(guī)格 | 500μg、1mg、5mg |
貨號 | EY-01Y21361 |
Cas No.: 26246-41-3
別名: N/A
化學名: 6,8-dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one
分子式: C11H10O5
分子量: 222.2
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM). It also inhibits DNA topoisomerase I when used at a concentration of 45 uM in B16F10 melanoma cells. Reticulol has antifungal activity against T. mentagrophyes with a MIC of 1.8 uM. It is cytotoxic against A427 human lung and B16F10 mouse melanoma cells at concentrations of 25 and 200 uM, respectively, and inhibits lung metastasis in mice.
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