產(chǎn)品屬性：

Cas No.: 138-59-0

別名: N/A

化學(xué)名: (3R,4S,5R)-3,4,5-trihydroxycyclohexene-1-carboxylic acid

分子式: C7H10O5

分子量: 174.15

溶解度: ≥ 17.4mg/mL in DMSO

儲(chǔ)存條件: N/A
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping Condition:Evaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Shikimic acid is a tri-hydroxy cyclohexene carboxylic acid implicated in biosynthesis of many compounds. The shikimate pathway is named after it. Shikimic acid can be used for the biosynthesis of the aromatic amino acids[1].

Shikimic acid can be isolated from the needles of a variety of plants and microorganisms, such as the Chinese star anise and the seeds of the sweetgum fruit. Shikimic acid can be used as a starting material for the synthesis of oseltamivir. Although shikimic acid is a biosynthetic intermediate existed in most autotrophic organisms general found in very low concentrations [1].

In vitro: In SH-SY5Y cells, 10nM, 10μM, and 10 mM shikimic acid showed antioxidant activity without exerting cytotoxic effects. In addition, shikimic acid protected the cells against H2O2-induced increases in ROS levels and DNA damage. Shikimic acidexhibited neuroprotective actions against oxidative stress-induced toxicity on SH-SY5Y cells [2].

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