產(chǎn)品屬性：
產(chǎn)品名稱 | PMQA |
規(guī)格 | 5 mg、10 mg |
貨號 | EY-01Y20372 |
Cas No.: 1263820-18-3
別名: N/A
化學名: N/A
分子式: C17H16N4O
分子量: 292.34
溶解度: N/A
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn2+ in living cells[1].After incubation with PMQA (20 μM) for 1 h, weak green fluorescence appeared, presumably caused by the probe capturing intracellular zinc from its native ligands since PMQA has high affinity for zinc[1].The response of PMQA to Zn2+ can be reversed by N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) or EDTA[1].When the stock solution of PMQA (0.1 mM in Tris Buffer) is kept at room temperature for a week, there is no significant loss of PMQA determined by HPLC analysis[1].[1]. Liangwei Zhang, et al. 8-Aminoquinoline-based ratiometric zinc probe: unexpected binding mode and its application in living cells. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3511-4.
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