產(chǎn)品屬性：
產(chǎn)品名稱 | Morin hydrate |
規(guī)格 | 500mg |
貨號 | EY-01Y19454 |
Cas No.: 6202-27-3
別名: N/A
化學(xué)名: 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one hydrate
分子式: C15H10O7.H2O
分子量: 320.25
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Morin hydrate is a plant flavonoid extracted from yellow Brazil wood with anti-oxidant properties. Previous studies have shown that morin hydrate could protect cells against oxygen radical damage.
In vitro: Morin hydrate at 75-100 μM protected against the oxidation of low density lipoprotein (LDL) induced by free radicals [1]. Morin hydrate at 100 μM concentration effectively inhibited Cu2+-induced oxidation of human LDL [2]. In cultured rat glomerular mesangial cells attacked by oxyradicals, the survival time of the cells was doubled with using morin hydrate [3]. 0.25 – 2.0 mM morin prolonged the survival of rat hepatocytes against free radical damage triggered by xanthine oxidase-hypoxanthine [4]. Morin hydrate could inhibit the amyloid formation by islet amyloid polypeptide and disaggregated amyloid fibers [5].
In vivo: In a 80 min ischemia rat model, treatment of morin at 2.5, 5.0 and 10 μmol/Kg reduced liver necrosis by 51.48 ± 9.94%, 66.55 ± 2.18%, and 79.37 ± 11.03%, respectively [3].
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