產品屬性:
產品名稱 | Peiminine |
規(guī)格 | 20mg |
貨號 | EY-01Y19437 |
Cas No.: 18059-10-4
別名: Vertieinon
化學名: (3S,4aS,6aS,6bS,8aS,9S,9aS,12S,15aS,15bR,16aS,16bR)-3,9-dihydroxy-9,12,16b-trimethyldocosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinolin-5(15bH)-one
分子式: C27H43NO3
分子量: 429.63
溶解度: DMF: 10mg/mL,DMSO: 15mg/mL,DMSO:PBS (pH 7.2) (1:30): 0.03mg/mL,Ethanol: 10mg/mL
儲存條件:
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.
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