產(chǎn)品屬性:
產(chǎn)品名稱 | Quercetin (hydrate) |
規(guī)格 | 5 g、10 g、50 g、100 g |
貨號(hào) | EY-01Y17767 |
Cas No.: 849061-97-8
別名: N/A
化學(xué)名: N/A
分子式: C15H10O7.XH2O
分子量: 302.2
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2)(1:4): 1 mg/ml,Ethanol: 2 mg/ml
儲(chǔ)存條件: Store at Room temperature
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.1,2,3 Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.2 It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days.1 Quercetin (30 μM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.31.Calgarotto, A.K., Maso, V., Junior, G.C.F., et al.Antitumor activities of quercetin and green tea in xenografts of human leukemia HL60 cellsSci. Rep.8(1)3459(2018)
2.Yuan, Y., Ma, S., Qi, Y., et al.Quercetin inhibited cadmium-induced autophagy in the mouse kidney via inhibition of oxidative stressJ. Toxicol. Pathol.29(4)247-252(2016)
3.Park, H.H., Lee, S., Son, H.Y., et al.Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cellsArch. Pharm. Res.31(10)1303-1311(2008)
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