產(chǎn)品屬性：
產(chǎn)品名稱 | V-9302 hydrochloride |
規(guī)格 | 10mM*1mL in DMSO、5mg、10mg、25mg、50mg、100mg |
貨號(hào) | EY-01Y17720 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C34H39ClN2O4
分子量: 575.14
溶解度: DMSO: 250 mg/mL (434.68 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5). V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells[1].[1]. Schulte ML, et al. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacyin preclinical models. Nat Med. 2018 Feb;24(2):194-202.
特別提醒公司產(chǎn)品僅供科研使用
