產(chǎn)品屬性：
產(chǎn)品名稱 | Unoprostone isopropyl ester |
規(guī)格 | 1mg、5mg、10mg、50mg |
貨號 | EY-01Y17587 |
Cas No.: 120373-24-2
別名: N/A
化學(xué)名: N/A
分子式: C25H44O5
分子量: 424.6
溶解度: DMF: 25 mg/ml,DMSO: 17 mg/ml,Ethanol: 17 mg/ml
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Unoprostone isopropyl ester (Rescula) is the clinically approved, prodrug form of unoprostone, which is a free acid analog of prostaglandin F2α (PGF2α). Both latanoprost and Rescula have been approved for the treatment of ocular hypertension. Both analogs of PGF2α are believed to act by increasing the rate of aqueous humor outflow through the uveoscleral pathway. Both drugs are believed to act as prodrugs, with endogenous esterases within the eye releasing the free acid active form of the drug. The typical does of Rescula (one drop of 0.12% solution) is nearly 100 times that of latanoprost. Rescula has very little activity on isolated DP or TP receptors, less than 0.0005% the activity of PGE2 on EP3 receptors, and about 3% of the activity of PGF2α on FP receptors.
特別提醒公司產(chǎn)品僅供科研使用
