產(chǎn)品屬性：
產(chǎn)品名稱 | sAJM589 |
規(guī)格 | 1mg、5mg、10mg、50mg、100mg |
貨號(hào) | EY-01Y17271 |
Cas No.: 2089-82-9
別名: N/A
化學(xué)名: N/A
分子式: C16H10N2O
分子量: 246.26
溶解度: DMSO: 5 mg/mL (20.30 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC50 of 1.8 μM[1].sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1].[1]. Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.
特別提醒公司產(chǎn)品僅供科研使用
