產(chǎn)品屬性：
產(chǎn)品名稱 | TH 5427 hydrochloride |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y17225 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C20H20Cl2N8O3.HCl
分子量: 527.79
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Potent nudix hydrolase 5 (NUDT5) inhibitor (IC50 = 29 nM). Displays >650-fold selectivity for NUDT5 over MTH1. Inhibits ATP synthesis, chromatin remodeling, gene expression and proliferation in progestin-treated breast cancer cells in vitro.Page et al (2018) Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat.Commun. 9 250 PMID:29343827
特別提醒公司產(chǎn)品僅供科研使用
