產(chǎn)品屬性：
產(chǎn)品名稱 | VU 0469650 hydrochloride |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y16702 |
Cas No.: 1443748-47-7
別名: N/A
化學(xué)名: N/A
分子式: C22H28N4O.HCl
分子量: 400.94
溶解度: DMSO: 100 mM,Ethanol: 50 mM
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Potent and selective negative allosteric modulator of mGlu1 (IC50 = 99 nM). Exhibits >100-fold selectivity for mGlu1 over mGlu2-8 and 68 other GPCRs, ion channels, kinases and transporters. Brain penetrant.Lovell et al (2013) N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: Identification of VU0469650, a potent and selective tool compound with CNS exposure in rats. Bioorg.Med.Chem.Lett. 23 3713 PMID:23727046
特別提醒公司產(chǎn)品僅供科研使用
