產(chǎn)品屬性:
產(chǎn)品名稱 | VTP-27999 TFA |
規(guī)格 | 10mM*1mL in Water、50mg、100mg、200mg、500mg |
貨號 | EY-01Y16503 |
Cas No.: 1013937-63-7
別名: N/A
化學(xué)名: N/A
分子式: C28H42ClF3N4O7
分子量: 639.1
溶解度: H2O: 10 mg/mL (15.65 mM); Ethanol: 2.4 mg/mL (3.76 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
VTP-27999 TFA is an alkyl amine Renin inhibitor; VTP-27999 TFA is useful for Hypertension and End-Organ Diseases.[1]. New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082.
[2]. Lanqi Jia? et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751
[3]. Ishchenko A, et al. Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25.
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