產(chǎn)品屬性：
產(chǎn)品名稱 | ZN-c3 |
規(guī)格 | 5 mg、10 mg |
貨號 | EY-01Y15843 |
Cas No.: 2376146-48-2
別名: N/A
化學名: N/A
分子式: C29H34N8O2
分子量: 526.63
溶解度: N/A
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
ZN-c3 is an orally active, highly potent and selective Wee1 inhibitor (IC50=3.9 nM). ZN-c3 can be used for the research of cancer[1].ZN-c3 IC50 is 103 nM in H23c cells[1].ZN-c3 (80 mg/kg; p.o.; 28 days) can effectively shrank tumors at 80 mg/kg as a single agent[1].ZN-c3 shows excellent exposures and bioavailability in the dog PK study[1].[1]. Huang PQ, et al. Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer [published online ahead of print, 2021 Aug 23]. J Med Chem. 2021;10.1021/acs.jmedchem.1c01121.
特別提醒公司產(chǎn)品僅供科研使用
