產(chǎn)品屬性:
產(chǎn)品名稱 | S-23 |
規(guī)格 | 5mg、10mg、25mg、50mg |
貨號 | EY-01Y14721 |
Cas No.: 1010396-29-8
別名: N/A
化學(xué)名: N/A
分子式: C18H13ClF4N2O3
分子量: 416.8
溶解度: DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 14 mg/ml,Ethanol: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
S-23 is a selective androgen receptor modulator (SARM). It binds to the AR (Ki = 1.7 nM) and induces AR-mediated transcriptional activation in CV-1 cells expressing the human receptor when used at a concentration of 10 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. It decreases testicular sperm concentration without reducing mounting behavior or the number of intromissions in intact rats when administered in combination with estradiol benzoate . S-23 (3 mg/kg) also increases preference for sexually active intact males when administered to ovariectomized female rats.
特別提醒公司產(chǎn)品僅供科研使用