產(chǎn)品屬性:
產(chǎn)品名稱 | Sparfosic acid trisodium |
規(guī)格 | 5mg、10mg、50mg |
貨號 | EY-01Y14725 |
Cas No.: 70962-66-2
別名: N/A
化學(xué)名: N/A
分子式: C6H7NNa3O8P
分子量: 321.06
溶解度: H2O: 250 mg/mL (778.67 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Sparfosic acid trisodium, is a potent inhibitor of aspartate transcarbamoyl transferase, with anti-tumor and antimetabolite activity. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis[1][2].[1]. Wang J, et al. Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug. Int J Oncol. 2015 Aug;47(2):782-90.
[2]. Angela D. Morris, et al. A New, Efficient, Two Step Procedure for the Preparation of the Antineoplastic Agent Sparfosic Acid
特別提醒公司產(chǎn)品僅供科研使用