產(chǎn)品屬性：
產(chǎn)品名稱 | Sterculic Acid |
規(guī)格 | 25mg |
貨號(hào) | EY-01Y14423 |
Cas No.: 738-87-4
別名: N/A
化學(xué)名: 2-octyl-1-cyclopropene-1-octanoic acid
分子式: C19H34O2
分子量: 294.5
溶解度: Soluble in chloroform, hexane, ethyl ether, methanol
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Sterculic acid is a cyclopropene fatty acid that has been found in S. foetida. It is an inhibitor of δ9-desaturase that decreases 9(Z)-myristoleic acid and increases oleic acid and 9(Z),11(E)-conjugated linoleic acid levels in the milk of lactating ewes when administered at a dose of 0.5 g per day. It also inhibits endoplasmic reticulum stress induced by 7-keto cholesterol in ARPE-19 cells when used at a concentration of 1 μM and prevents the formation of choroidal neovascularization when applied to eyes at concentrations of 0.1 to 10 mM in a rat model of macular degeneration induced by laser injury. Sterculic acid binds to a variety of kinases, including calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2), mammalian sterile20-related kinase 3 (MST3), and p90 ribosomal S5 kinase 4 (RSK4).
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