產(chǎn)品屬性:
產(chǎn)品名稱 | Vazegepant hydrochloride |
規(guī)格 | 1 mg、5 mg、10 mg、25 mg、50 mg |
貨號(hào) | EY-01Y14023 |
Cas No.: 1414976-20-7
別名: N/A
化學(xué)名: N/A
分子式: C36H47ClN8O3
分子量: 675.26
溶解度: H2O : 50 mg/mL (74.05 mM; Need ultrasonic)|DMSO : 50 mg/mL (74.05 mM; Need ultrasonic)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Vazegepant (BHV-3500) hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride is the first intranasal gepant for migraine. Vazegepant hydrochloride may be helpful in effective management of COVID-19 associated pulmonary inflammation[1][2][3].[1]. Moreno-Ajona D, et al. Gepants, calcitonin-gene-related peptide receptor antagonists: what could be their role in migraine treatment?. Curr Opin Neurol. 2020;33(3):309-315. [2]. Mehta PP, et al. Novel and Evolving Therapies for COVID-19 Related Pulmonary Complications. Am J Med Sci. 2021;361(5):557-566. [3]. Moreno-Ajona D, Pérez-Rodríguez A, Goadsby PJ. Gepants, calcitonin-gene-related peptide receptor antagonists: what could be their role in migraine treatment?. Curr Opin Neurol. 2020;33(3):309-315.
特別提醒公司產(chǎn)品僅供科研使用