產(chǎn)品屬性:
產(chǎn)品名稱 | Terbutaline |
規(guī)格 | 25mg、50mg、100mg、500mg |
貨號 | EY-01Y13532 |
Cas No.: 23031-25-6
別名: N/A
化學(xué)名: 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol
分子式: C12H19NO3
分子量: 225.3
溶解度: DMSO: slightly soluble,Methanol: slightly soluble,Water: 100 mM
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Terbutaline is a short-acting β2-adrenergic receptor (β2-AR) agonist and an active metabolite of bambuterol .[1],[2],[3] It binds to β1-, β2-, and β3-ARs (Ki = 31.3, 15.4, and 79.8 nM, respectively) and selectively increases adenylyl cyclase activity in CHO cell membranes expressing recombinant human β2- or β3- over β1-ARs at concentrations 100-fold greater than the respective Ki values.[1] Terbutaline inhibits histamine release induced by ovalbumin in isolated guinea pig lung mast cells.[2] It also inhibits airway obstruction induced by methacholine or leukotriene D4 in anesthetized guinea pigs.[4] Formulations containing terbutaline have been used in the treatment of asthma.
特別提醒公司產(chǎn)品僅供科研使用