產(chǎn)品屬性：
產(chǎn)品名稱 | Tefinostat |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y13192 |
Cas No.: 914382-60-8
別名: N/A
化學名: N/A
分子式: C28H37N3O5
分子量: 495.61
溶解度: DMSO: 100 mg/mL (201.77 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Tefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity[1].
HDAC
[1]. Zabkiewicz J, et al. The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias. Oncotarget. 2016 Mar 29;7(13):16650-62.
特別提醒公司產(chǎn)品僅供科研使用
