產(chǎn)品屬性:
產(chǎn)品名稱 | Ribociclib D6 |
規(guī)格 | 5mg、10mg |
貨號 | EY-01Y13144 |
Cas No.: 1328934-40-2
別名: N/A
化學(xué)名: N/A
分子式: C23H24D6N8O
分子量: 440.57
溶解度: N/A
儲存條件: N/A
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].[1]. VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10.
特別提醒公司產(chǎn)品僅供科研使用