產(chǎn)品屬性:
產(chǎn)品名稱 | Ribociclib D6 hydrochloride |
規(guī)格 | 5 mg |
貨號(hào) | EY-01Y12999 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C23H25D6ClN8O
分子量: 477.04
溶解度: N/A
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Ribociclib D6 (LEE011 D6) hydrochloride is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].[1]. VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10.
特別提醒公司產(chǎn)品僅供科研使用