產(chǎn)品屬性:
產(chǎn)品名稱 | Sorivudine |
規(guī)格 | 10mM*1 mL in DMSO、5mg、10mg、25mg、50mg |
貨號(hào) | EY-01Y12936 |
Cas No.: 77181-69-2
別名: N/A
化學(xué)名: N/A
分子式: C11H13BrN2O6
分子量: 349.13
溶解度: DMSO: 250 mg/mL (716.07 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Sorivudine (BV-araU) is an orally active synthetic pyrimidine nucleoside antimetabolite drug. Sorivudine derives its antiviral activity from selective conversion by a specific thymidine kinase present in certain DNA viruses to nucleotides, which can in turn interfere with viral DNA synthesis[1].[1]. Diasio RB, et al. Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase. Br J Clin Pharmacol. 1998 Jul;46(1):1-4.
[2]. Whitley RJ, et al. Sorivudine: a potent inhibitor of varicella zoster virus replication.Adv Exp Med Biol. 1996;394:41-4.
特別提醒公司產(chǎn)品僅供科研使用