產(chǎn)品屬性:
產(chǎn)品名稱 | RORγt Inverse agonist 3 |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y12874 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C29H31Cl2N5O4S
分子量: 616.56
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively[1].EC50: 0.22 μM (hRORγ), 0.15 μM (RORγt, human IL-17 cells)[1][1]. Amaudrut J, et al. Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1799-1806.
特別提醒公司產(chǎn)品僅供科研使用