產(chǎn)品屬性:
產(chǎn)品名稱 | TMP920 |
規(guī)格 | Free Sample (0.1-0.5 mg)、10mM*1mL in DMSO、5mg、10mg、50mg、100mg、200mg、500mg |
貨號(hào) | EY-01Y12882 |
Cas No.: 1421837-45-7
別名: N/A
化學(xué)名: N/A
分子式: C29H30N2O3
分子量: 454.56
溶解度: DMSO: 62.5 mg/mL (137.50 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
TMP920 is a highly potent and selective RORγt antagonist. TMP920 inhibits RORγt binding to the SRC1 peptide with an IC50 of 0.03 μM[1].[1]. Xiao S, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 2014 Apr 17;40(4):477-89.
特別提醒公司產(chǎn)品僅供科研使用