產(chǎn)品屬性：
產(chǎn)品名稱 | XY 018 |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y12814 |
Cas No.: 1873358-87-2
別名: N/A
化學(xué)名: N/A
分子式: C23H15F7N2O4
分子量: 516.36
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
RORγ antagonist (EC50 = 190 nM). Suppresses androgen receptor expression in prostate cancer cell lines. Also inhibits growth of tumors in androgen receptor-positive xenograft models.Wang et al (2016) ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nat.Med. 22 488 PMID:27019329 |Ndagi et al (2016) Re-emergence of an orphan therapeutic target for the treatment of resistant prostate cancer - a through conformational and binding analysis for RORγ protein. J.Biomol.Struct.Dyn. 36 1
特別提醒公司產(chǎn)品僅供科研使用
