產(chǎn)品屬性:
產(chǎn)品名稱 | ROR agonist-1 |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y12819 |
Cas No.: 2361528-74-5
別名: N/A
化學名: N/A
分子式: C21H20F6N2O5S
分子量: 526.45
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5[1].pIC 50: 7.5 (human primary TH 17 cells)[1][1]. von Berg S, et al. Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2. ACS Med Chem Lett. 2019 May 29;10(6):972-977.
特別提醒公司產(chǎn)品僅供科研使用