產(chǎn)品屬性:
產(chǎn)品名稱 | Tyrphostin AG30 |
規(guī)格 | 10mM*1mL in DMSO、2mg、5mg、10mg、25mg、50mg、100mg、200mg、500mg |
貨號(hào) | EY-01Y12796 |
Cas No.: 122520-79-0
別名: N/A
化學(xué)名: N/A
分子式: C10H7NO4
分子量: 205.17
溶解度: DMSO: 125 mg/mL (609.25 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].[1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42.
[2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93.
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