產(chǎn)品屬性:
產(chǎn)品名稱 | Spadin TFA |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y12206 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C92H143F3N26O24
分子量: 2126.36
溶解度: N/A
儲(chǔ)存條件: -20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Spadin TFA, a natural peptide derived from a propeptide released in blood, is able to block the TREK-1 (KCNK2 or K2P2.1) channel activity. Spadin TFA binds specifically to TREK-1 with an affinity of 10 nM. Spadin TFA is an efficient antidepressant in mice[1].[1]. Jean Mazella, et al. Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. PLoS Biol. 2010 Apr 13;8(4):e1000355.
特別提醒公司產(chǎn)品僅供科研使用