產(chǎn)品屬性:
產(chǎn)品名稱 | Swertiajaponin |
規(guī)格 | 20mg |
貨號(hào) | EY-01Y11011 |
Cas No.: 6980-25-2
別名: N/A
化學(xué)名: N/A
分子式: C22H22O11
分子量: 462.4
溶解度: Soluble in DMSO
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1].IC50: 43.47 μM (tyrosinase)[1][1]. Lee B, et al. Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase. Oncotarget. 2017 Sep 15;8(56):95530-95541.
特別提醒公司產(chǎn)品僅供科研使用