產(chǎn)品屬性：
產(chǎn)品名稱 | Shield-1 |
規(guī)格 | 10mM*1mL in DMSO、1mg、5mg、10mg、25mg、50mg、100mg |
貨號(hào) | EY-01Y10812 |
Cas No.: 914805-33-7
別名: N/A
化學(xué)名: N/A
分子式: C42H56N2O10
分子量: 748.9
溶解度: DMSO: ≥ 250 mg/mL (333.82 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein[1][2].[1]. Schoeber JP, et al. Conditional fast expression and function of multimeric TRPV5 channels using Shield-1. Am J Physiol Renal Physiol. 2009 Jan;296(1):F204-11.
[2]. Li S, et al. Effects of Shield1 on the viral replication of varicella zoster virus containing FKBP tagged ORF4and 48. Mol Med Rep. 2018 Jan;17(1):763-770.
特別提醒公司產(chǎn)品僅供科研使用
