產(chǎn)品屬性：
產(chǎn)品名稱 | TRAF-STOP inhibitor 6877002 |
規(guī)格 | 5mg、10mg、25mg、50mg |
貨號(hào) | EY-01Y10640 |
Cas No.: 433249-94-6
別名: N/A
化學(xué)名: N/A
分子式: C17H17NO
分子量: 251.32
溶解度: DMSO: 125 mg/mL (497.37 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction, compound VII, shows inhibition of NF-κB activation in RAW cells, extracted from patent WO2014033122A1[1]. TRAF-STOP 6877002 prevents the progression of established atherosclerosis in mice, reduces leukocyte recruitment and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques[2].[1]. Seijkens TTP, et al. Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542.
特別提醒公司產(chǎn)品僅供科研使用
