產(chǎn)品屬性：

Cas No.: 10310-32-4

別名: N/A

化學名: N/A

分子式: C29H34O6

分子量: 478.6

溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml

儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Tribenoside is a vasoprotective agent with anti-allergic and anti-inflammatory activities.1,2 It inhibits agonist-induced contractions in various isolated porcine venous preparations when used at concentrations ranging from 10 to 30 μg/ml.1 Tribenoside inhibits compound 48/80-induced histamine release in isolated rat peritoneal cells (EC50 = 10 μg/ml).3 It reduces decreases in proteoglycan levels and the severity of cartilage destruction in the inflamed joints in a rabbit model of surgically induced osteoarthritis when administered at doses of 100 and 200 mg/kg per day.4 Formulations containing tribenoside have been used in the treatment of hemorrhoids and varicose veins.1.Jaques, R.The activity pattern, in isolated veins, of a benzyl glucofuranoside derivative possessing combined anti-inflammatory and venotropic effectsPharmacology4(4)193-202(1970)

2.Jaques, R.The pharmacological activity of tribenosidePharmacology15(5)445-460(1977)

3.Rüegg, M., and Jaques, R.Tribenoside as an inhibitor of chemically induced histamine releaseExperientia30(4)399-401(1974)

4.Colombo, C., Butler, M., Hickman, L., et al.A new model of osteoarthritis in rabbits. II. Evaluation of anti-osteoarthritic effects of selected antirheumatic drugs administered systemicallyArthritis Rheum.26(9)1132-1139(1983)
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