產(chǎn)品屬性：
產(chǎn)品名稱 | Roflumilast-d4 |
規(guī)格 | 500 μg、1 mg |
貨號 | EY-01Y10531 |
Cas No.: 1398065-69-4
別名: N/A
化學(xué)名: N/A
分子式: C17H10Cl2D4F2N2O3
分子量: 407.2
溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Roflumilast-d4 is intended for use as an internal standard for the quantification of roflumilast by GC- or LC-MS. Roflumilast is a potent, cell-permeable inhibitor of PDE4 (IC50 = <1 nM for both human PDE4B and PDE4D).1 It is selective for PDE4, with IC50 values against other PDE forms being greater than 10 μM.
1.Card, G.L., England, B.P., Suzuki, Y., et al.Structural basis for the activity of drugs that inhibit phosphodiesterasesStructure12(12)2233-2247(2004)
特別提醒公司產(chǎn)品僅供科研使用
