產(chǎn)品屬性：
產(chǎn)品名稱 | Sekikaic Acid |
規(guī)格 | 1 mg |
貨號(hào) | EY-01Y10527 |
Cas No.: 607-11-4
別名: N/A
化學(xué)名: N/A
分子式: C22H26O8
分子量: 418.4
溶解度: DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲(chǔ)存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities.1,2,3 It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 μM.1 Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV; IC50 = 5.69 μg/ml).2 It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP; IC50 = 34 μM).31.Thadhani, V.M., Choudhary, M.I., Ali, S., et al.Antioxidant activity of some lichen metabolitesNat. Prod. Res.25(19)1827-1837(2011)
2.Lai, D., Odimegwu, D.C., Esimone, C., et al.Phenolic compounds with in vitro activity against respiratory syncytial virus from the Nigerian lichen Ramalina farinaceaPlanta Med.79(15)1440-1446(2013)
3.Majmudar, C.Y., H?jfeldt, J.W., Arevang, C.J., et al.Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300Angew. Chem. Int. Ed. Engl.51(45)11258-11262(2012)
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