產(chǎn)品屬性：
產(chǎn)品名稱 | STING18 |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y10408 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C29H27ClFNO5
分子量: 524
溶解度: DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:8): 0.11 mg/ml,DMSO: 5 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay).1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β production (EC50 = >30 μM) in THP-1 cells.|1. Siu, T., Altman, M.D., Baltus, G.A., et al. Discovery of a novel cGAMP competitive ligand of the inactive form of STING. Med. Chem. Lett. 10(1), 92-97 (2019).
特別提醒公司產(chǎn)品僅供科研使用
