產(chǎn)品屬性:
產(chǎn)品名稱 | Ro-0335 |
規(guī)格 | 5 mg、10 mg、25 mg、50 mg、100 mg |
貨號 | EY-01Y10159 |
Cas No.: 867365-76-2
別名: N/A
化學(xué)名: N/A
分子式: C21H13BrCl2FN3O4S
分子量: 573.22
溶解度: DMSO : 250 mg/mL (436.13 mM; Need ultrasonic)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates[1].[1]. Javanbakht H, et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 2010;86(2):212-219.
特別提醒公司產(chǎn)品僅供科研使用