產(chǎn)品屬性:
產(chǎn)品名稱 | Tuberculosis inhibitor 3 |
規(guī)格 | 5 mg、10 mg、25 mg、50 mg、100 mg |
貨號 | EY-01Y10206 |
Cas No.: 2219325-28-5
別名: N/A
化學(xué)名: N/A
分子式: C21H22F6N4O3S
分子量: 524.48
溶解度: DMSO : 27.5 mg/mL (52.43 mM; Need ultrasonic)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 μg/mL) against drug-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability[1].Tuberculosis inhibitor 3 (compound 2i, 50 mg/kg) shows acceptable PK properties with the AUC of 2489 h?ng/mL) is. The Tmax of Tuberculosis inhibitor 3 is 0.25 h[1].[1]. Kai Lv, et al. Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety. Eur J Med Chem. 2018 May 10;151:1-8.
特別提醒公司產(chǎn)品僅供科研使用