產(chǎn)品屬性：
產(chǎn)品名稱 | Thimerosal |
規(guī)格 | 10g、25g、50g |
貨號 | EY-01Y9621 |
Cas No.: 54-64-8
別名: N/A
化學(xué)名: N/A
分子式: C9H9HgO2S?Na
分子量: 404.8
溶解度: Ethanol: soluble,Water: soluble
儲(chǔ)存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Thimerosal is a mercurial antimicrobial agent.1,2 It is bacteriostatic against hemolytic streptococci and fungistatic against H. capsulatum, B. dermatitidis, and S. schenckii. Thimerosal (1-250 μM) induces apoptosis in HCN-1A human cortical neurons and various neuroblastoma cells.3,4 In vivo, thimerosal (80 mg/kg, i.p.) induces footpad swelling and dorsal skin contact dermatitis in a mouse model of pseudo-allergic reaction.5 Formulations containing thimerosal have been used as antiseptics and preservatives in vaccines.1.Morton, H.E., North, L.L., Jr., and Engley, F.B., Jr.The bacteriostatic and bactericidal actions of some mercurial compounds on hemolytic streptococciJ. Am. Med. Assoc.136(1)37-41(1948)
2.Deighton, F.J., Hall, N.K., and Larsh, H.W.Merthiolate treatment of pathogenic fungiJ. Clin. Microbiol.10(2)144-146(1979)
3.Baskin, D.S., Ngo, H., and Didenko, V.V.Thimerosal induces DNA breaks, caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblastsToxicol. Sci.74361-368(2003)
4.Dórea, J.G.Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccinesNeurochem. Res.36(3)927-038(2011)
5.Peng, B., Che, D., Hao, Y., et al.Thimerosal induces skin pseudo-allergic reaction via Mas-related G-protein coupled receptor B2J. Dermatol. Sci.95(3)99-106(2019)
特別提醒公司產(chǎn)品僅供科研使用
