產(chǎn)品屬性:
產(chǎn)品名稱 | Reveromycin A |
規(guī)格 | 250μg、1mg |
貨號(hào) | EY-01Y9651 |
Cas No.: 134615-37-5
別名: N/A
化學(xué)名: N/A
分子式: C36H52O11
分子量: 660.8
溶解度: DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 μM.
特別提醒公司產(chǎn)品僅供科研使用